Loretta Dorstyn Selected Research

Caspase 2

1/2019	Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling.
10/2017	Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity.
12/2016	Impaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice.
1/2014	Caspase-2 protocols.
12/2013	Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm-deficient mice.
3/2009	A tumor suppressor function for caspase-2.

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Loretta Dorstyn Research Topics

Disease

5	Neoplasms (Cancer) 01/2019 - 03/2009
2	Lymphoma (Lymphomas) 01/2019 - 03/2009
1	Inflammation (Inflammations) 01/2022
1	Neuroblastoma 01/2019
1	Hyperplasia 10/2017
1	Obesity 10/2017
1	Aneuploidy (Aneuploid) 12/2016
1	Premature Aging 12/2013
1	Genomic Instability 12/2013
1	Infections 04/2011
1	Necrosis 04/2011
1	Hypersensitivity (Allergy) 09/2009
1	Carcinogenesis 03/2009

Drug/Important Bio-Agent (IBA)

6	Caspase 2IBA 01/2019 - 03/2009
2	Cysteine Proteases (Cysteine Protease)IBA 01/2019 - 12/2016
2	Proteins (Proteins, Gene)FDA Link 12/2013 - 04/2011
1	Aspartic Acid ProteasesIBA 01/2022
1	Cysteine (L-Cysteine)FDA Link 01/2022
1	CaspasesIBA 01/2022
1	Epidermal Growth Factor (EGF)IBA 01/2019
1	RNA (Ribonucleic Acid)IBA 01/2019
1	CarbohydratesIBA 10/2017
1	AdiponectinIBA 10/2017
1	Glucose (Dextrose)FDA LinkGeneric 10/2017
1	AntioxidantsIBA 12/2013
1	sphingosine kinaseIBA 04/2011
1	Antiviral Agents (Antivirals)IBA 04/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2011
1	CytokinesIBA 04/2011
1	NF-kappa B (NF-kB)IBA 04/2011
1	MetalsIBA 09/2009